Gentamicin for peak identification
Gentamycin Solution
CAS: 1405-41-0
Molecular Formula: C60H127N15O26S
Gentamicin for peak identification - Names and Identifiers
Gentamicin for peak identification - Physico-chemical Properties
| Molecular Formula | C60H127N15O26S |
| Molar Mass | 1506.8 |
| Density | 1.000 g/cm3 |
| Melting Point | 218-237°C |
| Boling Point | 797.6°C at 760 mmHg |
| Specific Rotation(α) | D25 +102° |
| Water Solubility | Soluble in water |
| Solubility | 50 μg/mL in H2O |
| Appearance | White or white-like solid |
| Color | colorless to light yellow |
| Merck | 13,4403 |
| PH | 4.0-5.5 (0.1g/mL in H2O) |
| Storage Condition | 2-8°C |
| MDL | MFCD00270181 |
| Physical and Chemical Properties | Melting point 218-237°C |
| Use | For the treatment of sepsis, urinary tract infections, staphylococcal infections, endocarditis and other diseases |
Gentamicin for peak identification - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | S23 - Do not breathe vapour. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 2 |
| RTECS | LY2625000 |
| FLUKA BRAND F CODES | 3 |
| HS Code | 29419010 |
| Toxicity | LD50 in mice (mg base/kg): 430 i.p.; 485 s.c.; 75 i.v.; >9050 orally (Black) |
Gentamicin for peak identification - Upstream Downstream Industry
Gentamicin for peak identification - Reference
| Reference Show more | 1. Zhang Jipei, Wei Qinglan, Tan Hualong, et al. Study on drug resistance and aminoglycoside resistance genes of waterfowl-derived Escherichia coli in Guangdong [J]. Advances in Animal Medicine, 2016, 37(005):42-46. 2. Du Zixuan, Wang Yibo, Gao Lili, et al.. Effect of volume fraction of polyethylene glycol 400 in receiving solution on in vitro transdermal test of drugs [J]. Chinese Journal of Experimental Prescriptions, 2019, 025(001):196-200. 3. Gao Mingkun, Zhang Zhi, Qian Fang. Toxicology, Functional Test and Effect of Mixed Bacterial Preparation (BMX) on Fattening Pigs [J]. Feed Research, 2018, No.485(04):66-71. 4. Pan Wenjuan, Lin Jiafu, Wang Xiaotao, Guo Yidong, Chu Yiwen, Liu Chaolan. Isolation, Identification and Antibacterial Activity Determination of Actinomycetes from Tibetan Lakes [J]. Biotechnology Bulletin, 2020,36(07):97-103. 5. Yue Suijuan, Liu Jian, Gong Jiashun. Effects of Pu 'er Tea Tea Brown on Intestinal Flora of Rats [J]. Tea Science, 2016, 36(3):261-267. 6. Han Long, Ruan Guoxiang, Ma Jiexi, chemical mutagenesis and antibiotic resistance screening of vitamin B12 producing bacteria [J]. Fine and Specialized Chemicals, 2019, 27(01):40-43. 7. Liu Minfang, Cao Mengrui, Li Rongxu, et al. Isolation, Identification and Drug Sensitivity Analysis of Waterfowl-derived Salmonella in Some Areas of Guangdong [J]. Heilongjiang Animal Husbandry and Veterinary Medicine, 2018(10). 8. Dong Jing, zhang Lushan, Liu Shaochun, Zhang Guodong, Zhou Shun, Yang Qiuhong, Ai Xiaohui. Isolation, identification and drug sensitivity analysis of a strain of Klebsiella pneumoniae from Procambarus clarkii [J]. Journal of Huazhong Agricultural University, 2021,40(01):93-98 9. Zhang, Fangxing, et al. "The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice." Frontiers in microbiology 11 (2020): 2126.https://doi.org/10.3389/fmicb.2020.557342 10. [IF = 7.514] Ximo Wang et al. "A novel SERS sensor for the ultrasensitive detection of kanamycin based on a Zn-doped carbon quantum dot catalytic switch controlled by nucleic acid aptamer and size-controlled gold nanorods." Food Chem. 2021 Nov;362:130261 11. [IF = 4.235] Zhang Fangxing et al. "The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice." Front Microbiol. 2020 Oct;0:2126 12. [IF = 3.631] Shupei Liu et al. "Synergistic antimicrobial effects of photodynamic antimicrobial chemotherapy and gentamicin on Staphylococcus aureus and multidrug-resistant Staphylococcus aureus." Photodiagn Photodyn. 2020 Jun;30:101703 |
Gentamicin for peak identification - Introduction
Gentamicin binds to the 30S ribosomal subunit to cause code errors, blocking the transfer of peptidyl-tRNA(peptidyl-tRNA) from the receiving position to the donor point. The bactericidal effect of gentamicin on Pseudomonas depends on binding to the outer membrane part of the cell membrane to replace the existing cations, making the membrane unstable and forming cavities on the cell surface. Antibacterial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria.
Last Update：2022-10-16 17:13:52
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Gentamicin for peak identification
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Gadolinium chips
Epothilone B HOUSE STANDARD
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弱酸黄 2GL
Raw Materials for Gentamicin for peak identification